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Xylazine is a non-opioid animal tranquilizer that induces sedation and aids in pain relief. While xylazine is intended to be used in veterinary medicine, it has been increasingly found in combination with opioids such as fentanyl and linked to overdose deaths. Due to its impact on the opioid crisis, fentanyl mixed with xylazine has been declared an emerging threat by the White House’s Office of National Drug Control Policy. 

The following resources and webpages have more information on xylazine: 

Resources from the California Department of Public Health (CDPH) 

Resources from the Substance Abuse and Mental Health Services Administration (SAMHSA) 

  • Dear Colleague Xylazine Letter: This letter provides information about the consequences of xylazine exposure and what practitioners can do to mitigate harm. 

Resources from the Center for Disease Control and Prevention (CDC)